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NMN for Chronic Kidney Disease: What the Evidence Actually Shows

Category: renal | ICD-10: N18.9 | Evidence tier: mouse-only

What is Chronic Kidney Disease?

Chronic kidney disease is sustained reduction in kidney function (eGFR below 60 for over three months). Diabetes and hypertension are the leading causes in Malaysia.

NMN relevance: the published evidence

A few rodent studies show NAD+ precursors mitigate acute kidney injury. There is no completed human RCT of NMN in CKD with eGFR or proteinuria endpoints. Patients with advanced CKD must avoid unverified supplements due to clearance and contamination risks.

Questions to ask before supplementing

No dose validated in CKD.

Contraindications and red flags

Patients on dialysis or with eGFR under 30 should discuss any NMN question with a nephrologist before adding a supplement.

Bottom line for Malaysian patients

NMN is not registered with NPRA as a treatment for any specific condition; it is sold as a general health supplement. If you have chronic kidney disease, use this page as a question list for a registered medical practitioner before adding NMN to existing therapy. Read our safety guide for full red-flag context.

Related conditions

Cited references